| month | day | visitor | score | home | score |
|---|
| November | 5, 2004 | Hornets | | Spurs | |
| November | 8, 2004 | Spurs | | Rockets | |
| November | 9, 2004 | Mavericks | | Spurs | |
| November | 11, 2004 | Nets | | Spurs | |
| November | 14, 2004 | Blazers | | Spurs | |
| November | 15, 2004 | Jazz | | Spurs | |
| November | 17, 2004 | Spurs | | Warriors | |
| November | 18, 2004 | Hawks | | Spurs | |
| November | 19, 2004 | Grizzlies | | Spurs | |
| November | 20, 2004 | Hornets | | Spurs | |
| November | 23, 2004 | Mavericks | | Spurs | |
| November | 24, 2004 | Spurs | | Jazz | |
| November | 26, 2004 | Spurs | | Grizzlies | |
| November | 29, 2004 | Spurs | | Clippers | |
| December | 2, 2004 | Spurs | | Cavaliers | |
| December | 4, 2004 | Nuggets | | Spurs | |
| December | 5, 2004 | Rockets | | Spurs | |
| December | 7, 2004 | Magic | | Spurs | |
| December | 10, 2004 | Spurs | | Heat | |
| December | 18, 2004 | Spurs | | Wizards | |
| December | 19, 2004 | Nuggets | | Spurs | |
| December | 22, 2004 | Spurs | | Kings | |
| December | 23, 2004 | Hornets | | Spurs | |
| December | 26, 2004 | Spurs | | Blazers | |
| December | 28, 2004 | Spurs | | Jazz | |
| January | 4, 2005 | Spurs | | Blazers | |
| January | 6, 2005 | Spurs | | Knicks | |
| January | 7, 2005 | Bucks | | Spurs | |
| January | 10, 2005 | Spurs | | Wolves | |
| January | 11, 2005 | Nuggets | | Spurs | |
| January | 12, 2005 | Wolves | | Spurs | |
| January | 13, 2005 | Spurs | | Mavericks | |
| January | 14, 2005 | Grizzlies | | Spurs | |
| January | 15, 2005 | Spurs | | Wolves | |
| January | 16, 2005 | Spurs | | 76ers | |
| January | 18, 2005 | Spurs | | Bucks | |
| January | 20, 2005 | Raptors | | Spurs | |
| January | 22, 2005 | Rockets | | Spurs | |
| January | 24, 2005 | Spurs | | Celtics | |
| January | 25, 2005 | Wizards | | Spurs | |
| January | 29, 2005 | Pacers | | Spurs | |
| January | 31, 2005 | Bulls | | Spurs | |
| February | 2, 2005 | Cavaliers | | Spurs | |
| February | 4, 2005 | Spurs | | Mavericks | |
| February | 7, 2005 | Grizzlies | | Spurs | |
| February | 8, 2005 | Spurs | | Kings | |
| February | 9, 2005 | Clippers | | Spurs | |
| February | 17, 2005 | Spurs | | Pistons | |
| February | 18, 2005 | Sonics | | Spurs | |
| February | 20, 2005 | 76ers | | Spurs | |
| February | 23, 2005 | Rockets | | Spurs | |
| February | 24, 2005 | Spurs | | Sonics | |
| February | 25, 2005 | Wolves | | Spurs | |
| February | 26, 2005 | Spurs | | Hornets | |
| February | 27, 2005 | Pistons | | Spurs | |
| February | 28, 2005 | Spurs | | Nuggets | |
| March | 1, 2005 | Spurs | | Lakers | |
| March | 2, 2005 | Mavericks | | Spurs | |
| March | 4, 2005 | Spurs | | Magic | |
| March | 5, 2005 | Spurs | | Bulls | |
| March | 9, 2005 | Spurs | | Nets | |
| March | 10, 2005 | Suns | | Spurs | |
| March | 11, 2005 | Spurs | | Pacers | |
| March | 12, 2005 | Celtics | | Spurs | |
| March | 14, 2005 | Spurs | | Hawks | |
| March | 17, 2005 | Spurs | | Lakers | |
| March | 22, 2005 | Kings | | Spurs | |
| March | 23, 2005 | Spurs | | Wolves | |
| March | 29, 2005 | Spurs | | Raptors | |
| March | 31, 2005 | Heat | | Spurs | |
| April | 2, 2005 | Spurs | | Bobcats | |
| April | 5, 2005 | Spurs | | Sonics | |
| April | 8, 2005 | Spurs | | Suns | |
| April | 14, 2005 | Spurs | | Clippers | |
| April | 15, 2005 | Knicks | | Spurs | |
| April | 16, 2005 | Lakers | | Spurs | |
| April | 23, 2005 | Jazz | | Spurs | |
| April | 24, 2005 | Spurs | | Grizzlies | |
| April | 26, 2005 | Warriors | | Spurs | |
| April | 27, 2005 | Spurs | | Hornets | |
| April | 28, 2005 | Spurs | | Nuggets | |
| April | 30, 2005 | Spurs | | Rockets | |
| May | 3, 2005 | Bobcats | | Spurs | |
| May | 5, 2005 | Jazz | | Spurs | |